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Field
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for RNA viruses or DNA viruses. Experience with avian viruses and/or poultry models. Proficiency with vaccine platforms (live attenuated, vectored, subunit, mRNA/DNA) and immunoassays (ELISA, HI, VN
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up to __25_____lbs, Pushing/Pulling up to _50_____ lbs., Job Related Travel (conferences only), Hazardous Chemicals or fumes, Bloodborne/Airborne Pathogens/Recombinant DNA/Viral Vectors Shift Minimum
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the key duties of this position are the following: Performs in vivo animal experiments using mice, performing small craniotomies for injection of chemical and viral vectors, and for implantation of multiple
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CRISPR screens (CRISPRa/i, or dCas13 systems) Strong molecular biology skills (cloning, viral vector design, biochemistry) Experience with mammalian cell culture, viral production, and flow cytometry Prior
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large vector assembly towards Gb-scale genome synthesis Linda van Bijsterveldt – The van Bijsterveldt group aims to develop methods for building and stably transmitting synthetic chromosomes through
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MS for the characterisation of complex biopharmaceuticals including viral vectors for gene therapy delivery. You will evaluate and apply cutting-edge data analysis strategies to improve data usage and
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stereotaxic surgery to deliver drugs, neuronal tracers and/or viral vectors to manipulate functional brain circuits. Expose rats and/or mice to chronic intermittent hypoxic hypercapnia to model sleep apnea
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vectors studies, including vector design and cloning. RNA sequencing. Proteomics/transcriptomics and bioinformatics. PLA. Immunohistochemistry on brain sections. Surgery to implant electrodes and EEG
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or integrative physiology; in vivo mouse experimentation; viral vector approaches (AAV delivery, DREADDs, optogenetics); transgenic mouse strategies (Cre/Flp systems, intersectional genetics); or neuroanatomical
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management for science applications, focusing on integrating, organizing, and analyzing diverse data types to accelerate scientific discovery and innovation. Another goal is to develop and evaluate vector