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for injection of chemical and viral vectors, and for implantation of multiple stimulation and recording electrodes. Designs, executes, and analyzes research studies using intracranial EEG data from animals
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the absence of antiretroviral therapy (ART). Using nonhuman primates as a preclinical model of HIV/AIDS, we have shown that a single dose of adeno-associated virus (AAV) vectors at birth can result in stable
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, pathology, genomics, lab values, clinical notes) into unified, explainable vector representations for clinical decision support in oncology and cardiovascular medicine. Duration: 48 months | Coordinator: TUM
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the functional diversification of synapses in defined neural circuits. In this project, you will use an array of approaches, including CRISPR/Cas9 genome editing, viral vector technology, and quantitative super
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Cloning and Gene Editing: Design and construct CRISPR/Cas9 vectors for gene editing experiments. Perform cloning, plasmid preparation, and sequence verification. Conduct transfection and selection of edited
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viral vectors, electroporation with different repair templates, and evaluating strategies to enhance homology-directed repair. Through this work, you will gain advanced training in molecular and cell
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leverage them to build gene therapy vectors and regulatory-element directed expression systems toward the long-term goal of proximal digit and limb regeneration. Additional projects explore gene therapy
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project, investigating the pathogenic mechanisms and preventive measures of a group of vector-borne intracellular bacteria that cause emerging zoonoses. The successful candidate will utilize in vitro and in
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interaction with neuronal networks underlying memory storage and retrieval. For this, you will execute stereotactic surgeries to deliver viral vectors to specific brain regions implicated in memory. Furthermore
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background in neuroscience, neurophysiology, or molecular biology • Experience with EEG recordings, behavioral testing, viral vector delivery, or advanced microscopy Supplemental Qualifications • Ability