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Field
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that combines single-molecule, microfluidics, super-resolution techniques, and chemical/synthetic biology tools. PhD project: High Resolution Fluorescence Imaging of Protein Plasticity We are now seeking
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with these molecules. A successful candidate will be familiar with the differentiation of iPSC to myeloid cells, assays evaluating viral kinetics including p24 AlphaLISA analysis and high content imaging
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ubiquitin ligases, particularly the CRL4/CRBN system targeted by molecular glue degraders and PROTACs. By combining cryo-EM data with advanced computational modelling, the team aims to map how small molecules
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Max Planck Institute for Multidisciplinary Sciences | Gottingen, Niedersachsen | Germany | 3 days ago
, Dreier JE, Meisl G, Guido R, Knowles TPJ, Galvagnion C, Buell AK, Vendruscolo M, Michaels TCT. Global kinetic model of lipid-induced α-synuclein aggregation and its inhibition by small molecules. Proc Natl
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Max Planck Institute for Multidisciplinary Sciences | Gottingen, Niedersachsen | Germany | 3 days ago
, 28943-54 (2025) DOI : 10.1021/jacs.5c06971 The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers, S. Manikam, S. Ryazanov, A
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Student or Postdoc (f/m/d) for the project Theory and Algorithms for Structure Determination from Single Molecule X‑Ray Scattering Images Project description Single molecule X‑ray scattering experiments
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French National Research Institute for Agriculture, Food, and the Environment (INRAE) | Nantes, Pays de la Loire | France | 3 months ago
, for example, (iii) the study of the mobility of water and polymers in the presence of these molecules in controlled assemblies, single cell walls or tissues, (iv) the measurement of different properties
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cancer and neurodegenerative diseases. Duties and Responsibilities: Design and develop small molecules, nucleic acids and peptide therapeutics. Design, prepare and characterize nanoparticles. Employ state
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state-of-the-art technical equipment (e.g. next-generation single-molecule sequencing, flow cytometry with single-cell sorting, UHPLC-qTOF, 2720 core SMP server structure) and a stock of 40,000 different
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PhD Student (f/m/d) | NMR structure of AP-L complex of hIAPP and its effect on fibrils and membranes
Max Planck Institute for Multidisciplinary Sciences, Göttingen | Gottingen, Niedersachsen | Germany | about 2 hours ago, V. Singh Mithu, K. Giller, E. Nimerovsky, K. Overkamp, L.B. Andreas, S. Becker, C. GriesingerJACS 147, 28943-54 (2025) DOI : 10.1021/jacs.5c06971 The small molecule inhibitor anle145c