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. These coordinated hormonal activities influence not only the rate of cell division but also the duration and dynamics of each phase of the cell cycle. With the advent of advanced technologies, such as single-cell
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of the cell cycle. With the advent of advanced technologies, such as single-cell genomics and live-cell imaging, we can now explore hormone regulation at unprecedented single-cell resolution. Using these tools
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Research Project Nucleic acids are potent triggers of immune responses. The presence of virus-derived RNA or DNA molecules activates nucleic acid sensors inside the host cell, which stimulates protective
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data. We have developed in vivo single-cell CRISPR technologies to screen for dozens of molecular factors in vivo during developmental and disease. These technologies are a game-changer in the speed
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, including liposome preparations and confocal microscopy. For structural work, single particle cryo-electron microscopy is extensively utilized at the Biological Electron Cryogenic Microscopy Center
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spatial transcriptomics, genomics, or imaging-based methods. Experience with image analysis, single-cell or spatial omics data analysis. Familiarity with machine learning frameworks (e.g. PyTorch