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Field
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, biophysical and structural biology techniques including: In vitro evolution and de novo design of RNAs, Biophysical characterization using single (sm) molecule fluorescence and other techniques, such as smFRET
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that are properly folded and competent for protein translation. Force spectroscopy (optical and magnetic tweezers), single-molecule fluorescence, and bulk biochemical methods will be used to investigate how
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techniques of cryo-electron microscopy (cryo-EM), small angle X-ray scattering (SAXS), single-molecule force spectroscopy (SMFS), biochemistry, mutational analysis, cell culture, activity assays, et cetera
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project, which aims to explore the potential of paramagnetic complexes as solid-state quantum bits (qubits) for quantum information processing. In order to measure properties at the single-molecule scale
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Foundation, explores how pathogenic bacteria survive and cause infection. Working at the interface of genetics, chemical biology and machine learning, the team develops small molecules to disrupt key bacterial
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will involve collaboration with the Queen Elizabeth Hospital in Birmingham, and teams at the Universities of Oxford and Exeter, whole will bring expertise in single molecule and evolutionary biology to
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mechanisms. Performing experiments using mouse models. Applying molecular, cellular, and immunological techniques, including flow cytometry, imaging, and genomic approaches (e.g., single-cell RNA-seq
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based on proton quantum tunneling. The aim is to advance energy-efficient memcomputing technologies that integrate information processing and storage within single molecular systems, with potential
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Nanopore, with a strong emphasis on single-molecule chromatin fiber profiling (e.g. Fiber-seq). Applies and/or develops epigenomic and transcriptomic assays such as CUT&RUN and RNA-seq (including specialized
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capabilities for cell therapy (CAR-T cells, stem cells, etc.), monoclonal antibodies, and small molecule generation, in line with our vested interest in commercializing our discoveries so that they can reach