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Field
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lifetime microscopy and single-molecule localization microscopy, with the aim of enabling dynamic observation of living biological systems and nanostructures. This research lies at the interface of physics
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for mechanistic analysis of meiotic crossover interference and high resolution imaging of single molecule dynamics of chromosomes Basic Qualifications expertise in high resolution imaging, knowledge of mitotic
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organic methods for functional small molecules and polymers. The goal of projects in the Huang lab is to tackle critical societal challenges through precise structural control, efficient manufacturing, and
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organic methods for functional small molecules and polymers. The goal of projects in the Huang lab is to tackle critical societal challenges through precise structural control, efficient manufacturing, and
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niches that promote tumor progression using single cell and spatial approaches. These projects, and my laboratory, lie at the intersection of cancer genetics and tumor immunology, and at the interface
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decide the fate of their RNAs - whether to translate, store, or degrade them. Using biochemical reconstitution, fluorescent labeling, and single-molecule imaging, you will explore how molecular machines
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. Our lab applies advanced structural and biophysical methodologies including cryo‑electron microscopy (cryo‑EM), X‑ray crystallography, single‑molecule fluorescence, and enzyme kinetics to elucidate how
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following areas: -Biophysical instrumentation development: optical and mechanical design, simulation, development and control -Optical imaging; Single-molecule fluorescence and FRET; Lasers; Pump-probe
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of splicing regulation using an array of state of the art biophysical, structural, molecular and chemical biology techniques, including single molecule analyses of splicing complexes as pioneered by
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studies that looked at single bacteria RNA molecules or how well we are in reconstructing known bacterial genomes. Once we're confident our tool is accurate, we will use it to study the gut microbiome We're