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aggregates in biological fluids. The project aims to develop and refine a cutting-edge single-molecule detection platform that leverages molecular amplification and nanoscale sensing to identify and
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characterising protein identity and post-translational modifications at the single-molecule level. You will work as part of an interdisciplinary team developing new approaches to one of the key challenges in
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industrial partners. Our research combines chemical biology and biophysics to advance protein nanopore technologies for single-molecule sensing, with the long-term goal of enabling new approaches
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cardiovascular disease. The lab uses patient‑derived induced pluripotent stem cells (iPSCs) from healthy individuals and patients with cardiovascular conditions to study GPCR function, single‑molecule movement
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. The successful candidate will use biochemical, biophysical, and optical approaches, including advanced fluorescence microscopy (confocal, TIRF, single-molecule imaging), to dissect the molecular machinery
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of Chemistry and Biochemistry at The Ohio State University. The postdoctoral researcher will perform independent experiments in single-molecule and single-particle optical spectroscopy, centered around the
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the laboratory of Dr. Tai-Yen Chen. The Researcher will contribute to an active research program focused on single-molecule biophysics, super-resolution microscopy, quantitative analysis of membrane protein
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the laboratory of Dr. David Hoffman. The Researcher will contribute to an active research program focused on single-molecule biophysics, super-resolution microscopy, human stem cell engineering, membrane
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transport using 3D single molecule fluorescence microscopy and single particle tracking approaches (see Sau et al., 2025 Nature 640:821). Both astigmatism and MINFLUX microscopy will be applied to determine
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is located in Montpellier, a vibrant research hub on the Mediterranean coast, and hosts world-class expertise in advanced microscopy, including multiplexed imaging, single-molecule super-resolution