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Field
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responsible for designing, building, and utilizing single-walled carbon nanotube field effect transistor (SWNT FET) sensors to probe biological phenomena at the single-molecule level. See Turvey et al. (2022
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with these molecules. A successful candidate will be familiar with the differentiation of iPSC to myeloid cells, assays evaluating viral kinetics including p24 AlphaLISA analysis and high content imaging
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cancer and neurodegenerative diseases. Duties and Responsibilities: Design and develop small molecules, nucleic acids and peptide therapeutics. Design, prepare and characterize nanoparticles. Employ state
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, Recombinant protein expression and purification, biochemical and biophysical characterization of nucleic acids Computational model building and structure prediction Single-molecule fluorescence microscopy
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? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Molecular motors are key elements in the transport of molecules within cells
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decide the fate of their RNAs - whether to translate, store, or degrade them. Using biochemical reconstitution, fluorescent labeling, and single-molecule imaging, you will explore how molecular machines
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broad range of areas, including: Nanopore technologies for small-molecule diagnostics Single-molecule technologies for biopolymer analysis Programmable membrane proteins for nanoscale transport and
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–78 (2024). Reed, Brian D., et al. "Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device." Science 378, 186-192 (2022). Ameta, Sandeep, et al. "Darwinian properties
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disorder (RBD). Newly discovered molecular targets and disease-associated cellular phenotypes are used as readouts in drug screening approaches, to identify molecules that, after in vitro and in vivo
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Postdoctoral position to study Polo kinase and centrosome abnormalities in cancer and other diseases
approaches (e.g., super-resolution imaging, single molecule tracking, in vitro reconstitution, X-ray crystallography, and cryo-EM) to delineate the molecular bases and structural rules governing