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the identification genetic causes; a good example of this is work from Prof Hardy’s team on the discovery of the APP gene in Alzheimer’s disease (see review, J Neurochem. 2025 Jul;169(7):e70148. doi: 10.1111/jnc.70148
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and development of modelling and system identification methodologies with a focus on data efficiency. The successful applicant will work on industrially defined case studies from the area of
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for the computer simulation of electronically excited processes in molecules and materials. In the age of net-zero it is more important than ever to obtain a deep, molecular-level understanding of the working
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impaired DNA damage response. This proposal will focus on the investigation of genetic modifiers in RFC1 disease, leveraging the observation of naturally occurring genetic variation and controlled genome