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redox balance. Our studies explore how p53 integrates metabolic cues by acting as both a sensor and regulator of cellular metabolism. In parallel, we are identifying metabolic changes that promote tumor
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develop computational fluid dynamic (CFD) tools that make exascale computing accessible to a broader set of users. The successful candidate will develop a massively parallel solver, capable of running
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will have the opportunity to work with: High‑throughput functional genomics: pooled CRISPR and base‑editing screens, barcoded overexpression libraries, massively parallel reporter assays. Advanced cell
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complementary biochemical, biophysical, and cell biology techniques. Many proteins in nutrient signaling pathways are dysregulated in cancer, and in parallel with mechanistic structural work, we develop targeted
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(HPC): Experience with parallel computing (MPI, OpenMP, CUDA/HIP) or running workflows on supercomputing clusters. Software Engineering: Knowledge of version control (Git), containerization (Docker
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of multiple medicines across cellular mechanisms in parallel, ensuring accelerated assessment of existing and new therapies. Improving our understanding of the cellular basis of disease will help bridge the gap
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collaborating experimental research groups. Previous experience in computational modeling of atmospheric aerosols and parallel computing/software development is strongly desired. The term of appointment is based
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validated at CPPM. In parallel, the candidate will improve data reconstruction algorithms by using artificial intelligence techniques (e.g. neural networks), to optimize the separation between signal and
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. In parallel, the project aims to establish and apply a zebrafish avatar model to examine the role of selected aquaporins in cancer cell invasion and metastatic spread in vivo. Your job responsibilities
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learning algorithms for engineering systems Programming experience in FORTRAN, C, or C++ and scripting experience in Python or similar languages Experience with parallel computing environments and Linux