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Field
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protein engineering to develop agents based on our research into their photophysical properties and structure-function relationship. Finally, we are driving the development of specialized screening
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engineering of human embryonic stem cells, fluorescent knock-in line generation, and mechanistic studies of copper-regulated protein behavior. The successful candidate is expected to contribute immediately and
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methods to study the interactions between viral proteins and host proteins, which are characterized by a high degree of intrinsic disorder, with a focus on major human RNA viruses (measles, influenza, SARS
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, including genome engineering of human embryonic stem cells, fluorescent protein tagging strategies, clone validation, super-resolution microscopy, and cell-based biophysical studies of metal homeostasis
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. This project aims to design enzymes that do not exist in nature, combining physics-informed design principles, AI-driven protein engineering, and synthetic biology. About the position As a doctoral student, you
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collaborative framework, the candidate will lead the discovery, engineering, and deployment of lithium-binding proteins and peptides as highly selective biochelators for lithium recovery from complex leachates
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-binding proteins (IBPs) protect against freeze damage in polar regions by keeping the nucleation and growth of ice crystals in check. How this works exactly is not yet known. You will engineer IBPs de novo
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of Laws of 2018, item 1668, as amended). Experience in laboratory work in the field of molecular biology and biochemistry. Experience in protein–DNA interaction assays or genetic engineering methods is
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determination: Bradford, ELISA technique, multiplex LUMINEX technology Methods for the analysis of gene and protein expression data References: Alberts B. et al., Molecular Biology of the Cell. Sixth Edition
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of Bioenergetics and Protein Engineering (BIP-UMR7281) and the Laboratory of Bacterial Chemistry (LCB-UMR7283). Under the supervision of Dr. Stéphane Grimaldi, the researcher will produce and characterize enzymes