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context of the affected human tissue, and the power of our experimental models, this work will deliver urgently needed insights into the pathogenesis of YARS1-CMT. The project may also reveal shared
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. Extracting this information is still a challenge though, given its intrinsic multidimensional nature (time, perturbation, tissue position, cell state, statistical power). With modern probabilistic modelling
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, membrane proteins and structural biology is essential. The ability to work organized and independently with excellent communication skills is mandatory as well as proficiency in written and spoken English
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