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21 Apr 2026 Job Information Organisation/Company University of Bergen Department Michael Sars Centre Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1
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SARS-CoV-2. The position provides an opportunity to conduct ground-breaking research into the host response to virus infection and would suit an individual with experience in working with pathogenic
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structure–activity relationships (SAR) to optimize the potency, physicochemical and ADME properties, pharmacokinetics, safety, and in vivo efficacy of lead molecules. In collaboration with other scientists
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candidate vaccine and clinical cross cover with ongoing trials in the group, including SARS-CoV-2 and BCG challenge studies. You will play an active role in the design and execution of clinical trials
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The post holder will design and synthesise small molecules aimed at developing new therapeutic strategies for ASS1-deficient tumours. Your work will develop important structure–activity relationship (SAR
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biochemical and ADME/PK studies and data analysis Generating SAR hypotheses Performing empirical and structure-based target design Executing synthetic chemistry and troubleshooting Improving the potency
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, 7nAChR, 9* nAChR, GIRK1/2, GIRK1/4, etc.) Conducting biochemical and ADME/PK studies and data analysis Generating SAR hypotheses Performing empirical and structure-based target design Executing synthetic
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important structure–activity relationship (SAR) data across a number of different tumor types. The ultimate aim is to derive a number of lead compounds to take forward to advanced in vitro and in vivo studies
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Demonstrated expertise in small-molecule synthesis, optimization, and structure–activity relationship (SAR) studies Strong problem-solving skills and the ability to work independently within a collaborative
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vaccine platforms including mRNA vaccines (SARS-CoV-2) and novel delivery systems. The analysis of immune response involves detailed investigation of the cellular and molecular mechanisms controlling