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protein-protein interaction methods like the split ubiquitin yeast-two hybrid method and SIM microscopy training will be needed. The individual will report directly to the laboratory Principle Investigator
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techniques. Among the key duties of this position are the following: Performs multistage purifications including accurately making solutions and buffers. Homogenizes mouse tissues and prepares protein lysates
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biochemical assays. Carries out in vitro differentiation of iPSCs into neurons. Performs basic laboratory experiments in in vitro systems to study proteins and their functions. Assists with development
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analysis by the comparison of protein structures, conduct rigorous evaluations of the concordance of computational results to validation sets, and determine the origin of life on earth. Mentorship of 1-2
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. The Mickolajczyk laboratory is recruiting Postdoctoral Associates to engage in ongoing research projects relative to studying the mechanisms of pre-ribosome maturation by motor proteins and regulation and substrate
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will focus on structural characterization of B. thetaiotaomicron HTCS transcription factors; identification of ligands that bind to the extracellular domains of HTCS proteins; and investigations
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for the protein-membrane and protein-protein interactions required for the PA phosphatase function of catalyzing the dephosphorylation of PA to produce diacylglycerol. The ultimate goal is to identify effector
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will focus on structural characterization of B. thetaiotaomicron HTCS transcription factors; identification of ligands that bind to the extracellular domains of HTCS proteins; and investigations
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differentiation of iPSCs into neurons. Performs basic laboratory experiments in in vitro systems to study proteins and their functions. Assists with development of methodologies to express proteins in cultured
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stock solutions. Perform molecular biologic experiments that include Western blotting, protein-protein interaction assays, PCR, subcellular organelle isolation, and cell biologic studies. Communicate with