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-specific developmental timing and synchronization shape the formation of the human thalamocortical system. The project combines endogenous prenatal tissue, advanced human stem cell models, organoid and
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-unions remain significant clinical challenges, reflecting an incomplete understanding of the complex biological processes governing bone regeneration. Critical factors such as stem cell dynamics
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to develop 2D and 3D NMJ models for DM1, consisting of different combinations of patient-induced pluripotent stem cell (hiPSC)-derived neuronal and muscle cells, allowing the dissection of pathological
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post-mortem human brain tissue and map these states in relation to disease pathology in AD tissue. In parallel, immune responses will be modeled in human stem cell–derived systems to identify regulatory
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the Morphogenetic Micro Engineering laboratory of Dr. Stefan Giselbrecht and the BioMatt group of Dr. Matthew Baker. Organoids derived from pluripotent stem cells have an impressive ability to self-organize
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, you will generate and study human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and engineered cardiac tissues (ECTs). You will develop patient-specific cardiac models to identify