PhD position in the MSCA-DN “CanGoNano”: Synthesis and optimization of mRNA and Glyco-Lipid NanoParticles for targeted mRNA delivery

1 Apr 2026
Job Information

Organisation/Company

RiboPro B.V.

Research Field

Biological sciences » Other

Researcher Profile

First Stage Researcher (R1)

Positions

PhD Positions

Application Deadline

26 Apr 2026 - 23:59 (Europe/Amsterdam)

Country

Netherlands

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

40

Offer Starting Date

1 Oct 2026

Is the job funded through the EU Research Framework Programme?

Horizon Europe - MSCA

Marie Curie Grant Agreement Number

101226412

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

CanGoNano is a European Training Network funded in the framework of HORIZON Europe Marie Skłodowska-Curie Doctoral Networks (MSCA-DN), focusing on glyconanomaterials (GNM) as precision tools of unveil key insights on the triggering of the antigen presenting cells (APC) against cancer using antigenic peptides and mRNAs encoding for these peptides. Within  CanGoNano, Doctoral Candidates (DCs) will be equipped with a thorough multifaceted knowledge of the potential of glycoscience in cancer immunotherapy and the necessary transferable skills. CanGoNano will provide an international, intersectoral and interdisciplinary educational program, according to the EU Principles for Innovative Doctoral Training. This will put DCs in an advantageous position for job opportunities in both academia and industry.

Within the CANGONANO network, RiboPro BV is recruiting 1 Doctoral Candidate (DC) to carry out research in GlycoNanoMaterials for precision delivery of genetic material to antigen presenting cells. The position will be supervised by Alexander H van Asbeck (RiboPro, NL) and Co-supervised by Roland Brock (Stichting Radboud Universitair Medisch Centrum, NL) and Carmen Alvarez-Dominguez (Universidad Internacional de La Rioja, ES), and will offer candidates the opportunity to work at the forefront of glyconanotechnology to fill gaps in cancer immunotherapy, while benefiting from tailored training and international secondments across the consortium.

 

DOCTORAL CANDIDATE DC6: 

PROJECT TITLE. Synthesis and optimization of mRNA and Glyco-Lipid NanoParticles for targeted mRNA delivery.

PROJECT. The PhD project will focus on: 1) Design, enzymatic synthesis, and characterization of high-quality mRNAs encoding for the antigenic peptides; 2) Use of microfluidic mixing to produce size-defined LNPs; 3) Set up of the strategies for the CuAAC functionalization of LNPs with alkyne-tagged carbohydrate fragments/fluorescent probes, and for mRNA encapsulation; 4) Set up of LNP-mRNA formulated with adjuvants; 5) Training in enzymatic synthesis, microfluidics, bionanotechnology, carbohydrate & click chemistry, GNM formulation and anti-cancer activity. 

Host Institution: RiboPro B.V., R&D Department, the Netherlands. https://ribopro.eu  

Duration: 36 months, starting between October 2026.

Supervisor: Alexander H. van Asbeck (RiboPro, NL)

Co-supervisors: Roland Brock (Stichting Radboud Universitair Medisch Centrum, NL), Carmen Alvarez-Dominguez (Universidad Internacional de La Rioja, ES)

PLANNED SECONDMENTS. (1) University of Milan (IT), L. Lay, (II year, 2M), training on the synthesis of carbohydrate fragments for lectin targeting; (2) Universidad Internacional de La Rioja (ES), C. Alvarez, (II year, 3M), training on the anti-cancer capacity of GNM in vivo.

PhD School enrolment: Stichting Radboud Universitair Medisch Centrum https://www.radboudumc.nl/en/research/research-groups/biochemistry-of-integrative-systems https://www.ru.nl/en/imr/imr-doctoral-school

Where to apply

Website

https://cangonano.eu/

Requirements

Research Field

Biological sciences » Other

Education Level

Master Degree or equivalent

Skills/Qualifications

• Master degree in Molecular Biology, Biotechnology, Nanomedicine and/or Nanomaterial Science.
• Practical experience in molecular biology and molecular biology characterization techniques.
• Preferred but not mandatory experience with nanoparticle formulations.
• Strong analytical and problem-solving skills
• Good level of English proficiency (understood, spoken and written).
• Flexible, pro-active and team spirit

Specific Requirements

The selected candidate must meet the following requirements:

• Commit full-time to the research activity, unless authorization is granted by the European Commission for personal or family reasons.
• Carry out exclusively the research activities related to the specified research program
• Refrain from receiving any additional income beyond what is specified in the call.
• Agree to sign all necessary agreements concerning intellectual property rights.
• Maintain confidentiality in accordance with the regulations of the European Project.

Languages

ENGLISH

Level

Good

Internal Application form(s) needed
ANNEX A CanGoNano_General-call-for-applications_Annex-A-2026 website 16Mar2026_1.pdf
English
(892.61 KB - PDF)
Download
Additional Information
Benefits

Each recruited Doctoral Candidate will be offered a temporary gross research fellowship. The salary of the doctoral candidates (DCs) will be paid in accordance with the MSCA rules. Please, refer to the section “Applicable Unit Contributions” (page 118 and following) of the Horizon Europe Work Programme 2023-2025 for MSCA-DN actions, available at the following link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/… - call/2023-2024/wp-2-msca-actions_horizon-2023-2024_en.pdf 

Please, refer to the above-mentioned link and the MSCA-DN dedicated webpage: https://marie-sklodowska-curie-actions.ec.europa.eu/actions/doctoral-networks

 

Eligibility criteria

The DC position is open to candidates of any nationality, provided they strictly fulfil the eligibility requirements established for the enrollment through the Marie Sklodowska-Curie Action- Doctoral Network (MSCA-DN). Equal opportunities policy without distinction on the grounds of gender, racial or ethnic origin, religion or belief, disability, age or sexual orientation will be applied. Please, refer to the section “Recruited Researchers” (page 122 and following) of the Horizon Europe Work Programme 2023-2025 for MSCA-DN actions, available at the following link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/… - call/2023-2024/wp-2-msca-actions_horizon-2023-2024_en.pdf 

In particular, at the time of recruitment, applicants must comply with the following eligibility criteria:
➢ Experience: Applicants must not be already in possession of a doctoral degree. Applicants who have successfully defended their doctoral thesis, but who have not yet formally been awarded the doctoral degree, will not be considered eligible. Applicants must possess a five-years university degree (Master’s degree or equivalent). 

➢ Mobility rule: Applicants must not have resided or carried out their main activity (work, studies, etc.) in the country where the research training activities will take place for more than 12 months in the 3 years immediately prior to the recruitment date. 

Selection process

APPLICATION PROCEDURE 

The applicant must apply through the project website: www.cangonano.eu . Any other form of application will not be considered.

All applications will be checked for eligibility. Incomplete applications will be ignored. Applications will be in English. Applicants must complete/upload the data/documents and information through the project website www.cangonano.eu by following an 8-step application procedure. 

ASSESSMENT CRITERIA / EVALUATION CRITERIA 

Supervisors will pre-select candidates for each position, based on the information included in the application procedure that will be evaluated against the following criteria:
- Educational record;
- scientific quality of the applicant’s CV;
- expected individual impact and benefit to the fellow and to the project;
- previous experience in the subject of the CanGoNano research programme.

Shortlisted candidates will be invited for interviews with multiple supervisors from the network (online or in-person). Good level of English proficiency (understood, spoken and written) will be considered. Candidates will be notified of the outcome via the website.

Additional comments

The start of the employment is foreseen on 1st October 2026 (latest 1st November 2026), in accordance with the local regulations of the recruiting institution and in agreement with the local supervisors. Doctoral candidates must be enrolled in a doctoral programme leading to the award of a doctoral degree in at least one EU Member State or Horizon Europe Associated Country. Candidates must meet all admission requirements for the PhD programme at the recruiting institution. These requirements must be fulfilled at the start of the contract.

Candidates of all nationalities and genders are welcome to apply. 

In line with MSCA requirements, candidates must be willing to undertake international mobility during the fellowship, which is a mandatory requirement and may account for up to 30% of the contract duration. 

Please submit your application form, including CV, motivation letter, recommendation letter(s), and copies of relevant diplomas/documents via the project website: www.cangonano.eu by using the “APPLY NOW” function 

Candidates will be notified of the outcome via the website. 

For questions exclusively not addressed in the application guidelines available on the project website, candidates may contact the project team at cangonano@chimica.unifi.it . Replies will be provided only in such cases. 

Website for additional job details https://cangonano.eu

Website for additional job details

https://cangonano.eu

Work Location(s)

Number of offers available

1

Company/Institute

RiboPro B.V.

Country

Netherlands

Geofield

Contact

City

Oss

Website

https://ribopro.eu/

Street

Kloosterstraat 9

Postal Code

5349 AB

STATUS: EXPIRED

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