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Circuits Project description: Neuronal synapses are remarkably heterogeneous and dynamic structures that vary widely in molecular composition, nanostructure, and signaling strength. This rich variety
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carried out at the section Molecular and Cellular Neurobiology (MCN) . Recent studies have shown that in addition to neurons, glial cells play a major role in synaptic function. So far, it is unclear what
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generate, analyze, and integrate single-cell and spatial transcriptomic datasets across in vivo and in vitro systems. Your work will aim to identify developmental trajectories, human-specific molecular
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The research goal of PCF is to understand and to control liquids and their interfaces from molecular to macroscopic scales. Our research connects fundamental phenomena in static and dynamic wetting, nanofluidics
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chemistry, synthetic chemistry and passion for developing new molecular tools to study biomolecular interactions in a system-wide manner. Your job Molecules in our body constantly make interactions. This is
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version of the CRISPR Commons toolkit. You will be a key contributor to the ThermoCas9 engineering pipeline, responsible for the molecular and biochemical workflows that enable high‑throughput variant
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LSRI programme BioBeyond_NL. Bring your expertise in chemical biology, bioorganic chemistry, synthetic chemistry and passion for developing new molecular tools to study biomolecular interactions in a
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remains a major scientific and technological challenge. Your job This collaborative project between the Alta and Thevenon groups aims to address this challenge by developing molecular additives
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mechanisms that underlie memory consolidation during sleep, specifically examining how these processes are disrupted in the context of Alzheimer’s disease (AD). You will investigate how these molecular
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life come together. You will work in the modern laboratories of the Leiden Academic Centre for Drug research (LACDR). State of the art equipment for the project is available (cell culture, molecular