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and several natural isoforms (see Figure). Their mechanism targets lipopolysaccharide (LPS), with a 3D structure stabilized upon LPS binding, paving the way for effective, and low-toxicity analogs. In
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antibiotic resistance. Until now, cytochrome bd structures from from four different species (E. Coli, Mycobacterium smegmatis, Mycobacterium tuberculosis et Corynebacterium glutamicum) are available. The first
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, biophysics, computational biology, or a closely related discipline. Technical experience Existing familiarity with at least one of the following areas: Structural biology and/or cryo‑electron microscopy (cryo
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PhD position: Nanoengineering refractory compositionally complex alloys for extreme conditions (M/F)
will be performed using transmission electron microscopy (TEM) and time-of-flight secondary ion mass spectrometry (TOF-SIMS), providing access to atomic-scale structural and chemical information. Ion
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between chemistry and biochemistry. It is structured around two parallel PhD projects: one in chemistry (the position offered) and one in biochemistry, supervised by partner research team. This organization
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Description This PhD project aims to develop advanced software solutions for cryo-electron microscopy (cryo-EM) data analysis, modeling conformational heterogeneity, and identifying optimal binding candidates
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Inria, the French national research institute for the digital sciences | Villers les Nancy, Lorraine | France | 12 days ago
expertise in artificial intelligence, computational chemistry, structural biology, and experimental validation. Biomolecular function depends on both structure and dynamics. In particular, allostery is a
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: - EPI: interfacial electrochemistry; physicochemistry of surfaces and interfaces; electron spectroscopies - SORG: catalysis and heterocycles; fluorinated compounds and photo-induced processes; molecular
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topic: This position falls within the field of bioenergetics and protein biochemistry. The project aims to study the role of an original extra-membrane structural module involved in the mechanism
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Inria, the French national research institute for the digital sciences | Villers les Nancy, Lorraine | France | 3 days ago
, Google Cloud Spanner , and DuckPGQ ([Wolde23]) embody this shift, integrating tabular and graph-structured data within a single query framework. Replication techniques such as CRDTs ([Balegas18