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, by integrating image analysis and docking across multiple structural states. The new tools will be validated through their application to VCP/p97 data, a key protein that plays a central role in
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Inria, the French national research institute for the digital sciences | Villers les Nancy, Lorraine | France | 10 days ago
complexes. The PhD will be carried out within the newly created Inria project-team DELTA at the Inria Center of the University of Lorraine, focusing on computational biology and artificial intelligence
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) datasets of VCP/p97 and VCP/97–ligand complexes. This will enable obtaining detailed maps of conformational states associated with mini-protein engagement, allowing assessment of how designed binders control
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PhD position: Nanoengineering refractory compositionally complex alloys for extreme conditions (M/F)
refractory compositionally complex alloys (RCCAs) in the form of thin films, targeting their application in extreme environments such as those encountered in nuclear fusion reactors. The approach relies
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on the interplay between observations of natural phenomena, experimentation, and the modeling of the associated complex processes. ISTerre also conducts solid Earth observation missions, by hosting and
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advanced mesoscopic crystal plasticity provide powerful predictive capabilities, they remain computationally expensive when applied to realistic microstructures and large-scale structural analyses. A key
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Institut National des Sciences Appliquées de Lyon | Villeurbanne, Rhone Alpes | France | 10 days ago
introduces an important additional complexity: a strong fluid-structure coupling between the elastic pipe wall and the heavy internal fluid [6]. Depending on the frequency range and the circumferential modes
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the construction of 3D models of protein complexes inserted in membranes to quantuim chemistry calculations, including classical molecular dynamics simulations. The major points that will be under scrutiny during
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advanced mesoscopic crystal plasticity provide powerful predictive capabilities, they remain computationally expensive when applied to realistic microstructures and large-scale structural analyses. A key
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of objects, but current techniques are limited to small particles (micrometer to millimeter scale). In optics, the slowing down of light ("slow light") in structured media significantly amplifies radiation