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measurements: transepithelial resistance, muscle contraction Inflammation level measurements: RT-qPCR, ELISA, bioplex Immunocytochemistry, imaging and 3D reconstruction Flow cyrtometry Single-cell transcriptomic
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biology, biological data science, multi-omics, imaging, modelling, and AI-driven approaches PhD candidates will benefit from: Access to state-of-the-art experimental and computational platforms Strong
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, enabling clear observation of precursor activity prior to failure. High-resolution optical imaging will be used for detecting particle motions throughout the loading process using particle tracking and
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an essential role in inflammatory processes. Its overexpression is associated with chronic inflammatory diseases such as Crohn's disease. XIAP thus plays a key role in modulating the NOD2 inflammatory pathway
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, thermal cycling, shrinkage can trigger brittle failure. Improving the fracture resistance of these materials requires to deal with a multiscale process: macroscopic resistance depends on bond failure