2026-2201921-Post PHD position in Chemistry/Chemical Biology

Updated: about 1 month ago
Location: Limoges, LIMOUSIN
Job Type: FullTime
Deadline: 25 Mar 2026

24 Feb 2026
Job Information
Organisation/Company

Université de Limoges
Department

DRH-RECHERCHE
Research Field

Chemistry » Organic chemistry
Researcher Profile

First Stage Researcher (R1)
Positions

Postdoc Positions
Application Deadline

25 Mar 2026 - 23:59 (Europe/Paris)
Country

France
Type of Contract

Temporary
Job Status

Full-time
Offer Starting Date

1 Jun 2026
Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Our objectives are the design, synthesis and thorough biophysical and biological studies of a generation of PDAC-targeted photosensitisers like phenalenone. The design of the photosensitisers will ensure reactive oxygen species (ROS) generation under near visible photoactivation to treat deep-seated tumours without photodamage to healthy tissue. Targeting moiety for receptors overexpressed in PDAC cancer will be conjugated to the photosensitisers to specifically generate ROS at the tumour site. Different light sources and excitation mode will be tested to generate cytotoxic species (X-ray, ultrasound...)
The recruited post-doctorate fellow will be in charge of the synthesis of phenalenone-based photosensitisers and their coupling to targeting units developed within the consortium. He/she will
perform physico-chemical characterization of the photosensitisers, contribute to and supervise their
biological activities within the collaboration network. In collaboration with LUMA consortium, use of nanoscintillators, gold nanoparticles or biocompatible fluorescent organic NPs (FONPs) with different surface functionalization by photosensitizers and/or targeting agents should be developed for X-rays, ultrasound activations.   Synthesis of PFC nanodroplets containing O2 will lead to use ultrasound, for enhancement of PDT efficacy. 
He/she will communicate the progress of his/her work through consortium seminars, written reports and presentations at scientific congresses.


Where to apply
Website
https://www.unilim.fr/recrutement-post-doctorant-chimie-organique-chimie-molecu…

Requirements
Research Field
Chemistry » Organic chemistry
Education Level
PhD or equivalent

Skills/Qualifications

A PhD degree in molecular chemistry and a strong background in organic synthesis, skills and motivation for multistep synthesis, expertise in characterization techniques (NMR 1D and 2D, mass
spectrometry, absorption/emission spectroscopy, DLS, zeta potential…) and purification techniques (TLC, column chromatography, HPLC). 


Specific Requirements

An expertise in the synthesis and design, functionalization of nanoparticles (Gold…) would be a plus. 
High motivation to work in an interdisciplinary project at the interface of chemistry and biology.
Ability to conduct independent research and demonstrate open-mindedness, curiosity, and
organization. English written and oral communication skills.


Languages
ENGLISH
Level
Good

Research Field
Chemistry » Organic chemistry
Years of Research Experience
1 - 4

Additional Information
Eligibility criteria

According to French legislation, the applicant must have received a PhD degree no later than three years before the beginning of the contract


Selection process

CV, cover letter and copy of PhD degree to be sent by email mentioning reference of job offer at : drh-recrutement-recherche@unilim.fr

 

Any application submitted without a diploma will be considered inadmissible.


Website for additional job details

https://www.unilim.fr/recrutement-post-doctorant-chimie-organique-chimie-molecu…

Work Location(s)
Number of offers available
1
Company/Institute
LABCIS
Country
France
City
Limoges
Postal Code
87000
Street
123 Avenue Albert Thomas
Geofield


Contact
City

Limoges
Website

https://www.unilim.fr/recrutement-post-doctorant-chimie-organique-chimie-moleculaire/
Street

33 Rue François Mitterrand
Postal Code

87000
E-Mail

drh-recrutement-recherche@unilim.fr

STATUS: EXPIRED

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