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Field
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). Scope of tasks: The aim of the project is to determine, based on functional and proteomic data, the correlation between the level of proteins involved in key metabolic pathways and the observed changes in
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modelling, and machine learning approaches to analyse large-scale datasets, including bulk and single-cell sequencing, gene expression arrays, proteomics, and metabolomics. Working closely with senior
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, and spatial transcriptomics/proteomics on human cSCC samples; In vitro models and in vivo systems, including the immunocompetent SKH-1 mouse model of multistep photocarcinogenesis and xenograft models
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tools, bulk and single-cell RNA sequencing technologies, computational biology, and a background in tool development to accomplish the goals of this project. Additional experience in proteomics and
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., TCGA, TARGET, CCLE) Single-cell and spatial transcriptomics/proteomics High-throughput drug and genetic screens (e.g., DepMap, PRISM) Common bioinformatics resources and pipelines (e.g., NCBI, Ensembl
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of colorectal cancer (CRC) using organoid models. The researcher will focus on integrating dynamic mutations, live multiplexed transcriptomic imaging, and proteomic imaging at the cellular level to predict
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predicted by AlphaFold2 to complete the structural human proteome, analyse known and previously unknown binding sites and map pharmacophores to each site. This will form the foundation for future development
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at the Department of Biochemistry and the wider University of Oxford including a biophysical suite, proteomics, mass photometry and native mass-spectrometry equipment. This full-time fixed-term post is funded by
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The University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 5 days ago
for candidates with experience in background in one of these areas: proteomics, electrophysiology, microscopy, ion channels, gene therapy, synaptic physiology, biophysics advanced molecular biology, stem cells
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Job Description Project Description We invite applications for a postdoctoral position in experimental mass spectrometry-based proteomics, focused on peptide ionization, charge state behavior, and