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multifunctional protein. Despite its presence in almost all cell compartments, the key role of Spartin remains elusive, although a role in lipid droplets turnover and mitochondrial homeostasis has been highlighted
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and Responsibilities 75% - develop new protein engineering methods that leverage multivalency to achieve precision sensing and actuation in the design of molecular and cellular therapeutics 15
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, protein engineering, immunology, and/or cell biology; demonstrated ability to design and execute rigorous experiments and detailed protocols; strong organizational, analytical, problem-solving, and
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Summary A postdoctoral fellow position is available in the laboratory of Anna Moszczynska, Ph.D., to study cellular and molecular mechanisms underlying the anti-addictive properties of protein
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molecular and cellular biology (protein gel electrophoresis and western blotting, enzyme-linked immunosorbent assay, mammalian cell culture, PCR), and fundamental lab skills (stoichiometry/basic solutions
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About the project Systemic amyloidosis comprises severe protein misfolding diseases in which amyloid fibrils accumulate across multiple organs, leading to progressive dysfunction. AL (light‑chain
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will join an interdisciplinary team that applies a chemistry-first approach to explore mechanistic and functional aspects of protein regulation through post-translational modification. The lab is
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are lipid bilayer-enclosed particles released by most cell types that mediate cellular communication by delivering cargoes including proteins, nucleic acids, lipids, and metabolites. EVs have potential as a
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Vulnerabilities This project aims to explore the dynamic nature of the human replisome, with a focus on replisome protein architecture, replisome speed control, and replication stress responses in cancer cells. By
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proteins and nucleic acids and in particular RNA - preparation of in vitro cell-free translation extracts - purification of ribonucleic complexes suitable for structural studies by cryo electron microscopy