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to study the structural enzymology of proteins responsible for blood coagulation (https://biochem.slu.edu/faculty/dicerawp/ ) with the goal of unraveling the molecular architecture and mechanism
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transduction, or protein-protein interaction. Computer skills in data and statistical analyses are required. A proven record of productivity as demonstrated by recent first author publications in leading peer
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biology program focused on single particle cryoEM, X ray crystallography, protein biochemistry, membrane reconstitution, and quantitative biophysics. The lab has dedicated access to a cryoARM300 300 kV
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gene expression at the transcription level is limited. Despite the fact that most protein-coding mitochondrial genes are transcribed at the same rate, the levels of mature transcripts are different
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microscopy (cryo-EM) and tomography (cryo-ET), we aim to capture the transient, high-order assemblies that trigger signaling in response to stress. In addition to protein-protein interactions, the lab explores
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infrastructure for quantitative proteomics, molecular and functional genomics, bioimaging, and experimental model systems. The position is embedded in the Protein Research Group, which focuses on quantitative
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biological approaches, thereby facilitating an integrative research environment. The overarching goal of the research project is to gain an understanding of both protein synthesis and mechanobiology
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proteins and pathways implicated on disease pathogenesis. We are currently analyzing brain, CSF and blood, multi-omic data (transcriptomics, proteomics and metabolomics), from a large collection of well
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. Our research is focused on cell biology, spatial proteiomics and machine learning for bioimage analysis. The aim is to understand how human proteins are distributed in time and space, how this affects
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and Responsibilities 75% - develop new protein engineering methods that leverage multivalency to achieve precision sensing and actuation in the design of molecular and cellular therapeutics 15