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Field
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analysis in neurodegenerative disorders. Long-read RNA sequencing and analysis in neurodegenerative disorders. Brain tissue, plasma and iPSC/other protein analysis to confirm DNA/RNA findings. Duration. Full
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sciences, or a closely related field. Proven experience in omics data generation and analysis (transcriptomics, proteomics, metabolomics). Strong background in microbial physiology, protein/peptide
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RELION or cryoSPARC) and atomic model analysis. Skills in protein biochemistry (e.g., recombinant protein expression and purification), biophysical characterization (e.g., Bio-Layer Interferometry) and
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to) statistical modeling in protein folding, neurobiology, role of synthetic data in statistical analysis, machine learning and AI methods, causal inference in biomedical data. The appointment will be for up
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development, optimization, and validation of in vitro mammalian cell based assays that are related to metabolic diseases (such us cell culture, RNA/protein extraction qPCR, western blotting and other metabolic
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on the development of nanomedicine and gene therapy against chronic diseases and these specific aims to develop novel cancer nanomedicine using gene therapy to deliver functional proteins that tackle the dense
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nanopore- and optical-based platforms to study biomolecular processes at the single-molecule level, with a focus on proteins in native environments. You will take a hands-on role in experimental design, data
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biology techniques, including DNA manipulation, PCR, and molecular cloning. Conduct protein expression, purification, and characterization using methods such as spectrophotometry, HPLC, and SDS-PAGE. Design
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-of-the-art structural modelling and computational protein design approaches to understand and engineer enzymes that modify IgG Fc N-linked glycans. The successful candidate will use tools such as AlphaFold
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: · PhD or M.D. with a strong background and profound knowledge in the field of either molecular biology, immunology, cancer biology, experience in sequencing or protein structural data analysis is highly