-
analysis by the comparison of protein structures, conduct rigorous evaluations of the concordance of computational results to validation sets, and determine the origin of life on earth. Mentorship of 1-2
-
desirable. Experience with microbiology (cell culture and molecular genetics), transcriptomics, protein expression and purification and structural analysis are advantageous. Equipment Utilized Physical
-
for the protein-membrane and protein-protein interactions required for the PA phosphatase function of catalyzing the dephosphorylation of PA to produce diacylglycerol. The ultimate goal is to identify effector
-
desirable. Experience with microbiology (cell culture and molecular genetics), transcriptomics, protein expression and purification and structural analysis are advantageous. Equipment Utilized Physical
-
these iPSC lines, the generation and culturing of induced neurons from these iPSC lines, the isolation and analysis of RNA, protein and phospho-protein from these cultured cells, the molecular manipulation
-
techniques of cryo-electron microscopy (cryo-EM), small angle X-ray scattering (SAXS), single-molecule force spectroscopy (SMFS), biochemistry, mutational analysis, cell culture, activity assays, et cetera