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molecular biology and genetics, and experience with DNA-binding proteins are beneficial. They will use structural and biochemical approaches to determine how Exo7 recognises and processes DNA-protein
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how Exo7 recognises and processes DNA-protein crosslinks and how this pathway contributes to bacterial survival following antibiotic treatment. This work will be tightly coordinated with live-cell
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following treatment. NEWDAY-ABC is a hybrid intervention-implementation trial that will be carried out at four sites across Yorkshire and Greater Manchester. The parallel process evaluation will assess
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neuroplasticity, interdisciplinary neuro-immune research, high-throughput sequencing technologies, drug discovery and advanced therapeutics. We have excellent facilities to support our parallel use of pre-clinical
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information sciences. In parallel with basic research, we develop ideas and technologies further into innovations and services. We are experts in systems science; we develop integrated solutions from care
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bioinformatics. The role will be responsible for developing and characterising human dorsal root ganglia cultures to benchmark the newly developed iPSC derived organoid model systems. This will include processing
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workshops and producing accessible toolkit resources, with a proof-of-concept focused on diabetes prevention for women of South Asian and Black African heritage. In parallel, the post holder will work
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of multiple medicines across cellular mechanisms in parallel, ensuring accelerated assessment of existing and new therapies. Improving our understanding of the cellular basis of disease will help bridge the gap
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parallel, the Institute is developing state-of-the-art methods that integrate living tissues with synthetic scaffolds to model and repair organs. These efforts converge across three interrelated programmes