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( Nature 2024 , JACS 2026, Nature Protocols 2026). The proposed data rich experimentation will connect chemical structures to optimal reaction conditions. A competitive candidate will have a background in
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ziftomenib in acute leukemia models, Blood, 2026, doi: 10.1182 /blood.2025031201. Yao et al., Development of PRC1 Inhibitors Employing Fragment-Based Approach and NMR-Guided Optimization, J Med Chem. 2025 Jan
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particle trapping and related measurement techniques. Relevant skills include understanding of fundamental principles, design, optimization, computational electromagnetic, mechanical and thermal modeling
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scientifically diverse team to achieve assigned research objectives. Candidates with experience in the following areas are especially encouraged to apply: Development and optimization of next-generation sequencing
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(training provided). Design and optimize protocols for new biophysical assays to address complex cancer biology questions.– Example project: Science, 2023 Writing and submitting NIH training grants, including
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Development & Maintenance: Drive the development, optimization, and upkeep of the lab's computational tools and analysis pipelines, ensuring that they robustly support and accelerate the team's research
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for internal and external projects, bringing it up to industry standards. You will Develop and optimize the specificity assay for biologics, with technical support. Identify and assess innovative applications
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:1074-84). We also discovered that abiraterone works by conversion to a more active steroidal metabolite (Li, et al.Nature. 2015;523:347-51), that metabolism is pharmacologically modifiable to optimize