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- cellumation GmbH
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Field
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Dynamics group combines biochemistry, next-generation sequencing and computational analysis to understand how chromatin remodelling enzymes shape nucleosome positioning and genome regulation. We develop and
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state-of-the-art technical equipment (e.g. next-generation single-molecule sequencing, flow cytometry with single-cell sorting, UHPLC-qTOF, 2720 core SMP server structure) and a stock of 40,000 different
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, genomic, and epigenomic data of single-cell and bulk datasets, derived from various projects within the lab. Methodologies used in our laboratory include, but are not limited to, whole genome sequencing
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collaborative atmosphere, diversity and curiosity. Your tasks • Conduct data collection in field settings, the herbarium and in the laboratory, including DNA/RNA sequencing • Perform bioinformatic and
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genebank. Your tasks: Next Generation Sequencing for chromosome scale assembly (PACBIO Hifi + Kinnex, Hi-C) comparative genomics analysis gene functional analysis work in a team with IPK`s central NGS
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, genomic, and epigenomic data of single-cell and bulk datasets, derived from various projects within the lab. Methodologies used in our laboratory include, but are not limited to, whole genome sequencing
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) to analyze error sources (e.g. incomplete coupling, deprotection efficiency, sequence-dependent effects). Perform test to evaluate synthesis quality (e.g. fluorescence-based hybridization assays, library
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manufacturing Use and further develop CRISPR (epi-)genome editing methods in CAR T cells Using cellular (e.g., FACS) and molecular (e.g., single cell analysis, next generation sequencing) methods to characterize
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scenarios and implicit knowledge into artifacts, prototypes, and visual narratives. The designer will work across multiple initiatives, aiming to identify, experiment with, and ultimately document and share
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fibroblasts Design and optimize antisense oligonucleotides (ASOs) Perform cell transfections Extract RNA for RNA sequencing Analyze gene expression (qRT-PCR) Assess protein expression via Western blotting