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Field
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CRISPR perturbation of multiple metabolic genes at the single-cell level. - Determining the impact of metabolic gene perturbation on T-cell subsets at different ages by employing single-cell RNA sequencing
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of experimental autoimmune encephalomyelitis (EAE), a mouse model for the human central nervous system (CNS) autoimmune disease multiple sclerosis. We found that when the DCs express the self-antigen in a
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Max Planck Institute of Immunobiology and Epigenetics, Freiburg | Freiburg im Breisgau, Baden W rttemberg | Germany | about 2 months ago
approaches in the lab Develop original research ideas aligned with the lab’s vision Guide and supervise students (from Bachelor’s to PhD level) Present research findings at lab meetings, institute seminars
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, and adult cardiac editing • Molecular analysis of editing efficiency (PCR, qPCR, sequencing) • Tissue distribution and expression analysis • Contribution to translational studies in porcine cardiac
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sequence written along the string of nucleosomes? How do chromatin material properties are established during the cell cycle? Requirements: We aim at attracting the best talent and expect the following
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biochemistry, molecular genetics, biological materials, or related fields Applicants with strong research experience in transcriptome sequencing and analysis will be preferred. Prior experience in electron
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in transcriptome sequencing and analysis will be preferred. Prior experience in electron microscopy or mass spectrometry is advantageous but not required. Strong writing skills with a proven track
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in transcriptome sequencing and analysis will be preferred. Prior experience in electron microscopy or mass spectrometry is advantageous but not required. Strong writing skills with a proven track
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model of immune tolerance, effectively inducing temporary remission in autoimmune conditions like multiple sclerosis. Our goal is to "learn pregnancy’s code" to understand these natural protective
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. This mechanism is driven by small non-coding RNAs (piRNAs) that help to guide the effector proteins to their targets in a sequence specific manner. Hence, deciding which RNAs will be turned into piRNAs is a