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other team members in the lab and support projects focused on understanding the molecular basis of HD and validating therapeutic targets. Core duties will include breeding and weaning mouse models
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the field of molecular biology for cancer and ideally who has recent experience of RNA-sequencing, flow cytometry, molecular cloning, transduction and orthotopic animal models. Previous experience with
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. You will work closely with technical teams to incorporate transcriptomic, proteomic, and other omics approaches, ensuring alignment across models and high-quality data generation to support robust
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uses zebrafish and cell models, such as iPSC-derived retinal organoids, to further our understanding of how genes affect eye formation and retinal function. The research involves generating and
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the molecular signatures of proteostasis loss and identify early markers of proteostatic failure. The role combines wet-lab spatial biology with computational approaches. You will work across models and scales
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proteins in patient-derived cell models and will use induced pluripotent stem cells (iPSCs) from patients with HD to study the role of DDR proteins, in repeat expansion and contraction events. You will use