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Field
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dynamics during regeneration, aging, and cancer, and how these processes can be modulated. Our research is primarily conducted in vivo. We combine genetic mouse models (lineage tracing, conditional
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function using the Drosophila embryo as a model system. In the laboratory we extensively use advanced live-cell light microscopy to understand the behaviour of these organelles, as well as many standard
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appointment for 36 months based within the School of Medicine on the Ninewells Campus. The postholder will work between the Molecular Pathology Group lead by Professor Gorgoulis (Chair of Clinical Molecular
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Project overview Biological catalysis achieves remarkable chemical transformations using only a small set of coenzymes. Among them, flavins (FMN and FAD) stand out as uniquely versatile molecular platforms
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Ice and mixed-phase clouds remain a significant challenge for both observational methods and atmospheric modeling. However, recent advances in both areas offer promising opportunities for progress
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. The candidate will engage in cutting-edge research employing molecular and chemical biology techniques, including LC-MS metabolomics, flow cytometry, mouse model studies, genomics, proteomics and bioinformatics
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research under PI mentorship. Design, execute, and analyze translational studies focused on hereditary hearing loss and LOXHD1 dysfunction. Develop and characterize preclinical models, including mouse models
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, molecular biology, biochemistry, immunology, or related field, with a strong focus on murine myopathy models. Demonstrated experience in in vivo experimentation, including animal handling, dosing, tissue
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their EVs stimulate or regulate immune responses. They will also investigate if EVs can be used for cancer immunotherapy. The studies will be performed in model systems in vitro and in vivo. The studies will
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. - Conduct high-throughput serum proteomic analyses and integrate molecular datasets. - Validate candidate biomarkers in independent cohorts. WP3.2 – Integrated predictive modeling: - Develop integrative multi