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lifetime microscopy and single-molecule localization microscopy, with the aim of enabling dynamic observation of living biological systems and nanostructures. This research lies at the interface of physics
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at the Institute of Molecular Genetics of Montpellier (IGMM UMR5535, CNRS and University of Montpellier), in a highly international and interdisciplinary research environment. Montpellier is a dynamic Mediterranean
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, while preserving ultimate precision in single-molecule localization and access to key photophysical parameters (fluorescence lifetime, brightness, molecular dynamics). This approach paves the way toward
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presence or absence of TSPANC8 proteins. ADAM10 dynamics, as measured by SMT, will help to understand this molecular landscape. This project is funded by an INCA French grant. References - Fernandez et al
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performing atomistic simulations with Density Functional Theory and Molecular Dynamics. Data analysis and coarse graining in order to provide parametrisations for upper scale models (Kinetic Monte Carlo and
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, we observed size-specificity in the adaptation process at the phenotypic, genetic and mechanistic levels. However, we still do not understand the molecular pathways by which cell size shapes cellular