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William Dunn School of Pathology. The project will involve the mechanistic dissection of protein quality control pathways using quantitative cell-based assays, flow cytometry-based and imaging approaches
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quantitative cell-based assays, flow cytometry-based and imaging approaches complemented by biochemical and, where appropriate, structural methods. The successful candidate will be expected to work independently
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. Transport within cilia, the cell’s signalling and sensory antennae, is central to human biology. It enables these cell-surface organelles to assemble and dynamically change their proteome in response
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, is central to human biology. It enables these cell-surface organelles to assemble and dynamically change their proteome in response to stimuli, allowing them to transduce signals to the cell interior
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of direct relevance to computational single-cell and spatial genomics (bioinformatics, computer science, applied mathematics, physics, etc). You will have strong demonstrable competence with
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research projects, contributing to major funding applications, publishing high-impact research, and mentoring junior researchers. Applicants should hold a PhD/DPhil in cell biology, cancer biology, computer
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of large-scale biological datasets, applying statistical modelling and computational approaches to high-dimensional data such as bulk and single-cell sequencing, gene expression, proteomics, or metabolomics
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role focuses on the computational analysis and methodological development of third-generation and single-cell sequencing data to understand the role of transposable elements (TEs) in early mammalian
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interact with a set of challenging scenarios. This project is funded by the European Space Agency (ESA) and is in collaboration with Autodiscovery. TMNT will focus on a team of highly mobile Unitree A2
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environment at the University of Oxford. The programme integrates patient stratification using cerebrospinal fluid biomarkers, patient-derived induced pluripotent stem cell (iPSC) models, and pharmacological