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protein-protein interaction methods like the split ubiquitin yeast-two hybrid method and SIM microscopy training will be needed. The individual will report directly to the laboratory Principle Investigator
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computational analyses of large -omics datasets. Some of the techniques we use include standard cell and molecular biology techniques, flow cytometry, microscopy (standard imaging and FRET, FLIM, FRAP), high
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extensive experience in C. elegans genetics, molecular biology, and aging biology. Imaging using confocal microscopy. Certifications/Licenses Required Knowledge, Skills, and Abilities Experience in genetics
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techniques of cryo-electron microscopy (cryo-EM), small angle X-ray scattering (SAXS), single-molecule force spectroscopy (SMFS), biochemistry, mutational analysis, cell culture, activity assays, et cetera
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we use include standard cell and molecular biology techniques, flow cytometry, microscopy (standard imaging and FRET, FLIM, FRAP), high throughput genetic and chemical screens, single cell and spatial
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techniques, including histology, rodent brain dissection, stereotaxic surgeries for intracerebroventricular injections, and fluorescent microscopy. Must have effective oral and written communication skills
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gerbils and run behavioral experiments to assess the neural mechanisms of sensory-guided decision-making. Carry out post-experiment processing of brain tissue. Assist with microscopy and anatomical analysis
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underlying cerebrovascular deficits in Alzheimer’s disease pathogenesis, using biochemical methods, immunohistochemistry, fiberoptic spectroscopy, in vivo two photon microscopy and genetically modified mouse
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and molecular biology techniques, including cell culture, cloning, and DNA repair assays. Preferred Qualifications Familiarity with biostatistics, immunology, microscopy, computational genomics, and
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, Skills, and Abilities Strong knowledge of cryo-electron microscopy (3DEM) is required to curate and validate macromolecular structures. Experience with small molecule chemistry is a plus. Experience with