Postdoctoral Fellow in Biophysics (Index-Nr. 2411-25744)

9 Jan 2026
Job Information

Organisation/Company

Paul Scherrer Institut Villigen

Research Field

Physics » Biophysics

Researcher Profile

Recognised Researcher (R2)

Positions

Postdoc Positions

Country

Switzerland

Application Deadline

1 Mar 2026 - 23:59 (Europe/Zurich)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

41.5

Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme

Reference Number

2411-25744

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences within Switzerland. We perform cutting-edge research in the fields of future technologies, energy and climate, health innovation and fundamentals of nature. By performing fundamental and applied research, we work on sustainable solutions for major challenges facing society, science and economy. PSI is committed to the training of future generations. Therefore, about one quarter of our staff are post-docs, post-graduates or apprentices. Altogether, PSI employs 2300 people.

For the Nanodiffraction Group in the Multiscale Bioimaging Laboratory LMB, we are looking for a

Postdoctoral Fellow in Biophysics

Your tasks

In this position, you will work at the interface of experimental biophysics, structural biology, artificial intelligence, and pharmaceutical formulation science. Your main responsibilities will include:

• Characterization of biologics (antibodies, proteins, siRNA) in the presence of excipients using SAXS and complementary biophysical techniques
• Development and validation of a predictive pipeline for excipient–biologic interactions
• Integration of experimental SAXS data with AI-driven structural modeling to predict oligomerization behavior and excipient effects
• Close collaboration with the industrial partner Excelsus Structural Solutions to translate experimental workflows into formulation-related services
• Participation in experimental planning, quality control, and iterative excipient screening
• Presentation of scientific results at international conferences and contribution to peer-reviewed publications
• Co-supervision and scientific support of PhD and master’s students

 

Where to apply

Website

https://apply.refline.ch/673278/3815/yDjsJkAzra1UuxMq1mxxapEK1CA8Wvpu4KRMu5-hr5…

Requirements

Research Field

Physics » Biophysics

Education Level

PhD or equivalent

Skills/Qualifications

Your profile

Required qualifications: 

• PhD degree in Bioinformatics, Artificial Intelligence, Biochemistry, Biophysics, Pharmaceutical Sciences, or a related field
• Strong background in protein or nucleic acid biophysics and structural characterization
• Experience with computational modeling and data analysis
• Excellent command of English, written and spoken

Additional qualifications: 

• Experience in protein or biologics formulation
• Knowledge of SAXS, light scattering, or other solution-state biophysical characterization methods
• Familiarity with AI-driven modeling tools (e.g., AlphaFold Multimer, Rosetta) and/or molecular dynamics simulations
• Interest in translational research and industrial collaboration

Additional Information
Benefits

Our institution is based on an interdisciplinary, innovative and dynamic collaboration. You will profit from a systematic training on the job, in addition to personal development possibilities and our pronounced vocational training culture. If you wish to optimally combine work and family life or other personal interests, we are able to support you with our modern employment conditions and the on-site infrastructure. 

Your employment contract is limited to 2 years with the possibility of extension for 1 year.
 

Additional comments

For further information, please contact Dr Jinghui Luo, phone +41 56 310 47 64. 
Please submit your application online by 1 March 2026 (including a cover letter, a list of publications and addresses of referees) for the position as a Postdoctoral Fellow (Index-Nr. 2411-25744). 

Paul Scherrer Institute, Human Resources Management, Serdal Varol, 5232 Villigen PSI, Switzerland, www.psi.ch

Work Location(s)

Number of offers available

1

Company/Institute

Paul Scherrer Institut

Country

Switzerland

Geofield

Contact

City

Villigen PSI

Website

http://www.psi.ch/psi-home

Street

PSI West

Postal Code

5232

STATUS: EXPIRED

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