PhD Research Fellow in Biochemistry and Structural Biology (ref 294723)

Updated: about 2 months ago
Job Type: FullTime
Deadline: 01 Mar 2026

8 Feb 2026
Job Information
Organisation/Company

University of Oslo
Research Field

Biological sciences
Researcher Profile

First Stage Researcher (R1)
Positions

PhD Positions
Application Deadline

1 Mar 2026 - 23:00 (Europe/Oslo)
Country

Norway
Type of Contract

Permanent
Job Status

Full-time
Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The project focuses on biochemical and structural biology aspects of a protein redox network that is important for bacterial defense and survival e.g. during host infections. Firmicute bacteria, including the human pathogens Staphylococcus aureus and Bacillus anthracis have a unique bacterial low molecular weight thiol (bacillithiol), which is a key antioxidant compounds used to maintain the cellular redox balance. Under oxidative stress, bacillithiol becomes oxidised and regenerated by a bacillithiol disulfide reductase. Bacillithiol also protects cysteine residues from irreversible over-oxidation through post-translational bacillithiolation, which is reversed after stress by bacilliredoxin enzymes. 

The PhD candidate will use biohemical, biophysical, and structural methods to decipher reaction mechanisms of these enzymes, and to identify inhibitor leads with potential antimicrobial or antivirulence activity.

For more information and how to apply: https://www.jobbnorge.no/en/available-jobs/job/294723/phd-research-fellow-in-biochemistry-and-structural-biology


Where to apply
Website
https://www.jobbnorge.no/en/available-jobs/job/294723/phd-research-fellow-in-bi…

Requirements
Research Field
Biological sciences
Education Level
Master Degree or equivalent

Additional Information
Work Location(s)
Number of offers available
1
Company/Institute
Department of Biosciences
Country
Norway
Geofield


Contact
City

Oslo
Website

https://www.mn.uio.no/ibv/english/
Street

PO box 1072 Blindern
Postal Code

NO-0316
E-Mail

h.p.hersleth@ibv.uio.no

STATUS: EXPIRED

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