Postdoc Position in Gene Regulation

16 Jan 2026
Job Information

Organisation/Company

Utrecht University

Research Field

Biological sciences » Biological engineering
Biological sciences » Biology

Researcher Profile

Recognised Researcher (R2)

Application Deadline

10 Feb 2026 - 22:59 (UTC)

Country

Netherlands

Type of Contract

Temporary

Job Status

Not Applicable

Hours Per Week

40.0

Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Cell identity relies on correct gene expression, so the process of transcription is tightly regulated. During early elongation of RNA Polymerase II, it is likely to terminate. Early termination has a big impact on transcriptional output, but how it is regulated is poorly understood. The Vlaming lab aims to understand what drives early termination vs productive elongation. To this end, we use cutting-edge nascent-RNA sequencing techniques, high-throughput screening and precise genome editing.
Your job
This project aims to systematically identify and characterize regulators of early transcription termination. Potential approaches will involve pooled CRISPR screens, genome editing mouse embryonic stem cells to allow for rapid protein depletion, mapping transcriptional effects (RNA-seq, TT-seq, PRO-seq), proximity labeling approaches, ChIP, and the bioinformatic analysis of generated sequencing data. You are encouraged to bring your own expertise to the current project and contribute your own project ideas.
While working on this project, you will hone your technical skills as well as skills in project design, writing, presenting, supervising, and collaborating. As part of our team, you will contribute to an enthusiastic, collaborative and respectful environment, in which we can perform high-quality research together.

Where to apply

Website

https://www.academictransfer.com/en/jobs/357792/postdoc-position-in-gene-regula…

Requirements
Specific Requirements

You share our enthusiasm for gene regulation and are motivated to push beyond the boundaries of what we know. Furthermore, you meet the following criteria:

• you have obtained, or are on track to obtain, a PhD with first or co-author publications/preprints in a relevant field;
• you have a background in gene regulation, or in a closely related field;
• you bring experience with at least two, ideally more, of the following approaches: cell engineering, high-throughput assays, transcriptomics, genomics, sequencing data analysis;
• you are able to work independently, as well as collaboratively in a team;
• you are proficient in academic English, both spoken and written.

Additional Information
Benefits

• an independent postdoc position for an initial period of one year (1.0 FTE), with an extension of two additional years upon a positive evaluation;
• a gross monthly salary, depending on qualifications and experience, between € 3.546 and €5.538 in the case of full-time employment (salary scale 10 under the Collective Labour Agreement for Dutch Universities (CAO NU));
• 8% holiday pay and 8.3% year-end bonus;
• a pension scheme, partially paid parental leave and flexible terms of employment based on the CAO NU.

In addition to the terms of employment laid down in the CAO NU, Utrecht University also offers a range of its own schemes for employees. This includes arrangements for professional development , various types of leave, and options for sports and cultural activities . You can also tailor your employment conditions through our Terms of Employment Options Model. In this way, we encourage you to keep investing in your personal and professional development. For more information, please visit Working at Utrecht University .

Selection process

As Utrecht University, we want to be a home for everyone. We value staff with diverse backgrounds, perspectives and identities, including cultural, religious or ethnic background, gender, sexual orientation, disability or age. We strive to create a safe and inclusive environment in which everyone can flourish and contribute.
Knowledge security screening can be part of the selection procedures of academic staff. We do this, among other things, to prevent the unwanted transfer of sensitive knowledge and technology.
If you are enthusiastic about this position, just apply via the "Apply now" button! Please enclose:

• your letter of motivation describing what excites you about the position and what makes you a good candidate; if you have not yet obtained your PhD degree please also include what remains to be completed;
• your curriculum vitae;
• the names, email addresses and phone numbers of at least two references (no reference letters needed at this point);
• a copy of your PhD certificate, if already obtained; otherwise, please indicate in your motivation letter what requirements remain.

If this specific opportunity isn’t for you, but you know someone else who may be interested, please forward this vacancy to them.
Some connections are fundamental – Be one of them
#FundamentalConnection

Additional comments

For more information, please contact Hanneke Vlaming at h.vlaming@uu.nl .
Do you have a question about the application procedure? Please send an email to science.recruitment@uu.nl .

Website for additional job details

https://www.academictransfer.com/357792/

Work Location(s)

Number of offers available

1

Company/Institute

Universiteit Utrecht

Country

Netherlands

City

Utrecht

Postal Code

3584CH

Street

Padualaan 8

Geofield

Contact

City

Utrecht

Website

http://www.uu.nl/

Street

Domplein 29

Postal Code

3512 JE

STATUS: EXPIRED

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