Melatonin-mediated modulation of mesenchymal stromal cells in scaffold supplemented with human platelet lysate for tissue regeneration

Università degli studi di Brescia, Italy

Updated: 17 days ago
Deadline: 07 Apr 2026

19 Mar 2026
Job Information
Organisation/Company

Università degli studi di Brescia
Research Field

Medical sciences
Researcher Profile

Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)
Application Deadline

7 Apr 2026 - 14:00 (UTC)
Country

Italy
Type of Contract

To be defined
Job Status

Not Applicable
Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Melatonin has attracted interest for its properties.It can regulate stem cell behavior by modulating redox balance,mitochondrial activity,inflammatory mediators & differentiation pathways.Recent studies highlight its incorporation into biomaterial scaffolds to improve biological performance.Scaffolds act as carriers for cells and bioactive factors,guiding tissue regeneration.Human platelet lysate rich in growth factors & cytokines,enhances proliferation,survival & reparative capacity of human mesenchymal stromal cells.This project investigates how melatonin modulates hMSC behavior within a scaffold enriched with hPL to promote a time-controlled therapeutic response during tissue healing.It will evaluate the effects of melatonin on hMSC viability & oxidative stress in a 3D microenvironment & whether melatonin modulates hPL bioactivity by influencing growth factor signaling through in vitro morphological,immunohistochemical & biochemical analyses


Where to apply
Website
https://www.unibs.it/it/ateneo/amministrazione/concorsi/bandi-il-conferimento-d…

Requirements
Additional Information
Eligibility criteria

Eligible destination country/ies for fellows:

  • OTHER

Eligibility of fellows: country/ies of residence:

  • OTHER

Eligibility of fellows: nationality/ies:

  • OTHER

Website for additional job details

https://www.unibs.it/it/ateneo/amministrazione/concorsi/bandi-il-conferimento-d…

Work Location(s)
Number of offers available
1
Company/Institute
Università degli studi di Brescia
Country
Italy
Geofield


Contact
City

Brescia
Website

https://www.unibs.it

STATUS: EXPIRED

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