1 Apr 2026
Job Information
- Organisation/Company
CIML2000- Research Field
Medical sciences » Cancer research- Researcher Profile
Leading Researcher (R4)- Positions
Postdoc Positions- Application Deadline
15 May 2026 - 00:00 (Europe/Paris)- Country
France- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
38- Offer Starting Date
2 Apr 2026- Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Team of Sandrine Roulland, Centre d’Immunologie de Marseille-Luminy (CIML), France
Main missions and activities
The postdoctoral researcher will join Sandrine Roulland’s team at the Centre d’Immunologie de Marseille-Luminy (CIML). The group investigates genomic and transcriptomic deregulations involved in the development and progression of human lymphomas.
The successful candidate will contribute to a research program aimed at generating, interpreting, and developing in vivo CRISPR Cas9 genetic screens in Primary and cell line models of T-cell lymphomas and characterize their oncogenic dependencies, and functionally validate them using CRISPR-based genetic perturbation approaches.
Through integrative analyses, the team also seeks to decipher the biological mechanisms underlying relapse and therapeutic resistance. The researcher will actively contribute to data analysis, synthesis of results, and preparation of scientific publications related to the project.
The postdoc will work in close collaboration with a network of bioinformaticians specializing in the design and development of data analysis pipelines for functional genomics, including CRISPR and single-cell approaches.
Responsibilities
Development of CRISPR-Cas9 genetic screens in vivo on primary and cell line lymphoma models
Generate functional genomics data (CRISPR and single-cell) using human lymphoma patient-derived models (In vivo and in vitro).
Perform and finalize the analysis of CRISPR screening experiments and generate graphical representations of results.
Validate and consolidate identified targets through CRISPR-based perturbation assays, combined with transcriptomic and proteomic analyses in both human and murine models.
Analyze, interpret, and communicate research findings with collaborators and contribute to scientific publications (manuscript writing, figure preparation).
Where to apply
roulland@ciml.univ-mrs.fr
Requirements
- Research Field
- Medical sciences » Cancer research
- Education Level
- PhD or equivalent
Skills/Qualifications
Proficiency in genetic perturbation methods using CRISPR in vitro and in vivo.
Experience with proteomic analyses by mass spectrometry and flow cytometry.
Ability to maintain scientific and methodological awareness relevant to the research theme.
Demonstrated autonomy, initiative, organizational skills, scientific rigor, adaptability, and enthusiasm.
Excellent communication skills for interdisciplinary collaboration with biologists and bioinformaticians.
Proven ability to draft scientific reports, manuscripts, and figures in English.
Fluency in written and spoken scientific English.
Specific Requirements
Strong interdisciplinary interactions with both the biology research team and the CIML bioinformatics/statistics platform.
- Languages
- ENGLISH
- Research Field
- Medical sciences » Cancer research
Additional Information
Benefits
- Mutuelle santé collective obligatoire avec participation de l’employeur à hauteur de 50 % pour le socle de base et à hauteur de 50 % dans la limite de 5 € pour les options
- Prévoyance collective facultative avec participation de l’employeur à hauteur 7 € pour le socle de base »
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- CIML Inserm U1104
- Country
- France
- City
- Marseille
- Postal Code
- 13008
- Street
- Parc de Luminy
- Geofield
Contact
- City
Marseille- Website
http://www.ciml.univ-mrs.fr/- Street
Parc Scientifique et Technologique de Marseille-Luminy- Postal Code
13009
roulland@ciml.univ-mrs.fr
STATUS: EXPIRED
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