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, ultimately leading to axonal degeneration in a manner shared across aaRS-linked CMT. To test this, we will perform high resolution spatial transcriptomics and proteomics analyses in unique nerve biopsies and
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this, we will perform high resolution spatial transcriptomics and proteomics analyses in unique nerve biopsies and iPSC-motor neurons derived from YARS1-CMT patients. Multimodal bioinformatics processing
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