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). - activities: For each of the objectives listed, the doctoral research will encompass (i) a literature review, (ii) the application of classification analysis methods (principal component analysis or cluster
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the course of a year. These logbooks will serve as a basis for follow-up during the T1 and T2 interviews. Chronothematic analysis: This component will aim to identify the emergence of non-predefined themes and
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LevelMaster Degree or equivalent Skills/Qualifications English level B2; Use of data collection and analysis tools (design of online questionnaires, statistical processing software (SPSS, R…), discourse
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) for the synthesis of natural alterin and analogues. Depending on the stereochemistry obtained by Marfey analysis, the synthesis of -OH Dab will be carried out from 5-hydrox-yectoin using the protocol developed by
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, meshfree/particle approaches). Conduct sensitivity analysis and model reduction to identify key drivers of persistence. Use models to simulate in silico scenarios (immune modulation, relapse, clearance vs