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transitions in Streptomyces , and to understand their evolutionary and ecological benefits. Why this project is exciting Streptomyces are among the most prolific natural producers of antibiotics and other
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for degradation? At the core of mRNA nuclear export works an evolutionary conserved machinery centered on a large protein complex: TREX. While we recently uncovered a mechanistic framework of the core of this
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, NLRs trigger a response leading to cell death upon pathogen recognition. A recent evolutionary model proposes that NLRs have evolved from single units (singleton NLRs) able to both detect and respond
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