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- WROCŁAW UNIVERSITY OF ENVIRONMENTAL AND LIFE SCIENCES
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Field
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determinants underlying natural catalytic strategies of drug-target heme enzymes and their bioresistance. Our approach of engineering redox-active Trp(s) resulting in controlled Trp radical(s) as substrate
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systems (proteins, enzymes, membranes, and complexes) Integrate AI/ML approaches with physics-based simulations to accelerate discovery and improve predictive fidelity Contribute to cross-scale modeling
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‑guided optimizations across languages (Julia/JACC, Mojo/MLIR, Rust/LLVM). Incorporate Enzyme-based automatic differentiation and multi-language IR tooling for AI‑driven analysis. High‑Productivity
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research environment. The following experience will strengthen your application: Experience with enzyme-constrained or proteome-constrained metabolic models, and integration of proteomics or other omics data
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field from a recognized university. Requirement Strong expertise in fungal biotechnology and biodiversity Strong expertise in the extraction and characterization of enzymes Demonstrated expertise with
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) surgeries to model ischemic stroke in mice. Conduct biochemical assays to analyze lipid signaling, enzyme expression, and oxidative stress markers in brain tissue. Perform Western blotting, PCR
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projects aimed at characterizing new microtubule-modifying enzymes. Biochemistry (western blots, protein purification, enzyme assays, etc.) Molecular biology (qPCR, cloning, mutagenesis, etc.) Cell culture
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pathophysiology that results from genetic mutations in mitochondrial proteins, chromatin regulators, and metabolic enzymes. We interpret our experiments in the context of curated clinical phenotypes and validate
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Independently conduct molecular cloning, mutagenesis, protein purification, protein characterization, protein engineering and design, enzyme kinetics, protein crystallization. Microbiology assays, including C
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enzyme superfamilies required for triterpenoid biosynthesis, carry out combinatorial biosynthesis using a rapid and powerful transient plant expression system established in the Osbourn lab (in Nicotiana