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Field
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, with strong training across genome engineering, chromatin biology, and gene regulation in diverse model systems. Extensive experience in CRISPR-based genome editing, mutant line generation, and molecular
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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the USA. - Multilingual working environment: French, English, Spanish, Portuguese (Brazilian) - Participation in the Summer Schools is compulsory and may begin as early as the 2026 edition, which will
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al. Molecular Biology of the Cell, 4th edition. New York: Garland Science; 2002. Chapter 3: Proteins Chapter 8: Manipulating Proteins, DNA, and RNA Chapter 10: Membrane Structure Westermeier R., Naven
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, yeast and mammalian cells including primary cells from affected CDG patients.•The generation of cellular models using CRISPR/Cas9 gene-editing and other techniques.•Development and optimization
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(the template can be downloaded from the institute’s website: www.biochim.ro/announcements ). Additional comments Bibliography Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell, 4th edition. New
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thus regulating cellular glycosylation (Voss et al . (2014), EMBO J), the laboratory has more recently employed state-of-the-art genome editing, tailored cellular models and advanced proteomics and
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research focus on generalisation. Still, the issue of domain dependence often remains. Recently there has been an increased interest in model combination and model editing, for example through
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for translational research. By combining super-resolution microscopy with genome editing and advanced image analysis, we systematically assess how these methods can reveal disease-associated cellular phenotypes