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mechanism has been mostly studied only in vitro using chemical disruption and has never been directly demonstrated in vivo following noise-induced TTS. Moreover, tip link disruption is currently undetectable
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in a living organism, especially when the damage occurs repeatedly over a lifespan. The central hypothesis of this PhD project is that repeated temporary threshold shifts interfere with tip link repair
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Single-cell high-throughput sequencing, extracting huge amounts molecular data from a cell, is creating exciting opportunities for machine learning to address outstanding biological questions
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