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Field
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deregulations involved in the development and progression of human lymphomas. The successful candidate will contribute to a research program aimed at generating, interpreting, and developing in vivo CRISPR Cas9
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understood. While RNA is often assumed to be degraded upon damage, our recent work demonstrated that human cells can repair RNA breaks generated by CRISPR ribonucleases and that this pathway can be harnessed
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developing next‑generation CRISPR tools designed specifically for crop improvement? Then this role as research assistant might be just for you! The Laboratory of Microbiology (Wageningen University & Research
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Massachusetts Institute of Technology | Cambridge, Massachusetts | United States | about 2 hours ago
site-specific genome integration (e.g., CRISPR/Cas9, RMCE), next-generation sequencing, computational methods/tools for analysis, and statistics; background in molecular biology, synthetic biology
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human health. Within this mission, the Iorio Group works at the intersection of computational biology, functional genomics, and precision oncology, integrating machine learning, large-scale CRISPR
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proficient in epigenome-related techniques (DNA methylation and/or histone modifications) and their analysis. Alternatively, the candidate comes with an expertise in CRISPR-based epigenetic editing
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will apply include endogenous protein tagging by CRISPR and integrases, in-cell interaction proteomics by proximity labeling, subcellular localization by spatial proteomics and fluorescence microscopy
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chromatin accessibility, CRISPR based gene and epigenetic perturbation, and deeply phenotype human cohorts to define causal mechanisms driving post infectious and post tuberculosis lung disease. Postdoctoral
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cloning for CRISPR gene editing. The successful candidate will be expected to carry out these tasks as routine experiments, working both independently and as part of a team. The post holder will be required
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interests, you will have the opportunity to work with: High‑throughput functional genomics: pooled CRISPR and base‑editing screens, barcoded overexpression libraries, massively parallel reporter assays