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Field
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chromatin accessibility, CRISPR based gene and epigenetic perturbation, and deeply phenotype human cohorts to define causal mechanisms driving post infectious and post tuberculosis lung disease. Postdoctoral
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cloning for CRISPR gene editing. The successful candidate will be expected to carry out these tasks as routine experiments, working both independently and as part of a team. The post holder will be required
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of São Paulo (UNIFESP), in Brazil, aims to investigate how CRISPR-Cas9-mediated genetic modification of Invariant Natural Killer T (iNKT) cells can modulate their antitumor activity and therapeutic
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interests, you will have the opportunity to work with: High‑throughput functional genomics: pooled CRISPR and base‑editing screens, barcoded overexpression libraries, massively parallel reporter assays
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research, CRISPR technologies, novel humanized mouse models of neuromuscular disorders and state-of-the-art delivery technologies for nucleic acid therapeutics, as well as research on disease mechanisms (see
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for Neuroscience . The Verstreken lab is developing advanced multielectrode array systems to mimic human brain circuits relevant to neurodegenerative disease. They are also conducting advanced CRISPR screens
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, chromatin analysis, single-cell epigenomics). Stem cell research (iPSC culture, differentiation, organoids, neural models). Experience with CRISPR, organoid technology, or mRNA therapeutics is a plus. Proven
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-targeting CRISPR systems (Zolboot et al. in preparation), and single-cell, isoform-sensitive measurements of translation in vivo (Ribo-STAMP; Sison et al. Nature 2026). Using these tools, we have identified
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homeostasis. The Wang group has been using Cre-loxP/Flp-frt and CRISPR strategy to manipulate genes of interest and use chemogenetics/optogenetics strategy to manipulate neuronal activities in specific neuron
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Max Planck Institute of Molecular Cell Biology and Genetics, Dresden | Dresden, Sachsen | Germany | about 6 hours ago
collaborative research to dissect the regulation of proteome remodeling using genetics and proteomics approaches. Depending on your background and interests, you may contribute to: High-throughput CRISPR