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procedures and the provision of animal care, in accordance with Decree-Law No. 113/2013. - Proven knowledge of molecular biology techniques (e.g., qPCR, Western blot, ELISA, genetic editing using CRISPR-Cas9
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CRISPR/Cas9 techniques to manipulate DNAm at promising sites. Lead the write-up of scientific papers to disseminate research findings through high-impact journal publications and conference presentations
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 3 days ago
. Experience with genome editing technologies such as CRISPR is a plus. * For dry-lab applicants: Ph.D.-level training and research experience in analyzing multi-omics next-generation sequencing data is required
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of these genes to the osteoarthritis phenotype. Analyses include CRISPR/Cas9 genome editing in mouse, scRNA-seq, spatial profiling, WES/WGS, and tissue culture. The candidate should be prepared to analyze gene
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develop and apply innovative technologies for analyzing immune memory (Krausgruber 2020 Nature), for high-content CRISPR screening (Bock 2022 Nature Reviews), and CAR T cell engineering (Datlinger 2025
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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, septins and other host factors. Use in vitro motility assays to reconstitute and analyse motor‑driven transport of virions. Manipulate host cells (e.g., siRNA, CRISPR, inhibitors) to test how specific
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, single-cell RNA-Sequencing, CRISPR genome editing, and general molecular biology techniques. Huntsman Cancer Institute is committed to cancer prevention, care, and survivorship for all communities within
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Perform in vivo studies in humanized mouse models Utilize advanced technologies such as CRISPR/Cas9-based gene editing and prime/base editing on human primary cells and HSCs, and in patient-derived
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signalling, cell biology, mouse neurobiology, CRISPR gene-editing or proteomics to investigate the function of the PINK1 kinase in neurons and the brain. The overarching goal of the Muqit lab is to undertake