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Max Planck Institute for Multidisciplinary Sciences, Göttingen | Gottingen, Niedersachsen | Germany | about 5 hours ago
Number: 101227450 LipAgg Doctoral Network project The LipAgg project seeks to unravel the structural complexities of amyloid protein-lipid aggregates and investigate their role in pathological aggregation
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on high-resolution cryo-electron microscopy to determine the structures of lipidic alpha-synuclein (αSyn) amyloid fibrils. The aggregation of αSyn as well as its interaction with lipid membranes play a key
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elucidation of membrane protein complexes and integrates fundamental cell biology and structural biology by cryo- electron microscopy. The lab has a strong track record in investigating scramblases and their
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laboratory (bio-)chemistry, beamtimes at synchrotrons, data analysis and comparison to expected physics. Due to the complex structure of the composite droplets, we expect emerging effects which can contribute
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Identifying and validating models for complex structures featuring nonlinearity remains a cutting-edge challenge in structural dynamics, with applications spanning civil structures, microelectronics
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10.01.2022, Academic staff The Chair of Computational Modeling and Simulation (CMS) at Technical University Munich invites applications for the position of a Research Assistant (m/f/d) for performing fundamental research in the frame of the project DrawOn funded by the Bavarian State Ministry...
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, by integrating image analysis and docking across multiple structural states. The new tools will be validated through their application to VCP/p97 data, a key protein that plays a central role in
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Inria, the French national research institute for the digital sciences | Villers les Nancy, Lorraine | France | 10 days ago
complexes. The PhD will be carried out within the newly created Inria project-team DELTA at the Inria Center of the University of Lorraine, focusing on computational biology and artificial intelligence
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) datasets of VCP/p97 and VCP/97–ligand complexes. This will enable obtaining detailed maps of conformational states associated with mini-protein engagement, allowing assessment of how designed binders control
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, chemically demanding, and operationally complex. By developing porous structures that enable fluids to separate naturally through capillary and interfacial effects, this project aims to advance a more